Biotechnologist (All Experience Levels) – Cell Therapy & Mammalian Manufacturing - Night Shift
Location: Portsmouth, NH, USA.
At Lonza Portsmouth, you won’t just make medicine — you will help shape the future of how it is made. Our site is uniquely positioned at the intersection of personalized Cell Therapy and large-scale Mammalian biologics manufacturing. In one facility, we produce both patient-specific, life-saving cell therapies and high-volume biologic medicines used by people around the world. That means your career here doesn’t live in a single box — it grows across platforms, technologies, and modalities.
What You’ll Get
Meaningful Patient Impact: From individualized therapies made from patient-donated cells to large-scale biologics produced in 2,000L, 6,000L, & 20,000L bioreactors, everything you do directly supports our purpose.
Cross-Platform Career Growth: As Lonza expands both Cell Therapy and Mammalian manufacturing, you’ll have opportunities to grow across modalities, technical depth, and leadership tracks.
World-Class Training: Develop expertise in Grade B aseptic gowning, cell therapy processing, and large-scale mammalian systems (Upstream & Downstream).
Nights and Weekend shifts include additional pay.
Comprehensive Benefits: Medical, dental, vision, 401(k), and global Lonza benefits: https://www.lonza.com/careers/benefits.
What You’ll Do
Your responsibilities will scale with your experience and may span both Cell Therapy and Mammalian Manufacturing depending on business needs and your career path.
Cell Therapy Focus
Work in Grade B cleanrooms requiring full sterile gowning.
Perform aseptic processing inside laminar flow hoods using strict sterile technique.
Receive, process, expand, and cryopreserve patient-derived primary cells.
Execute flawless cGMP documentation for individualized patient batches.
Mammalian Manufacturing Focus
Operate mammalian cell culture bioreactors (2,000, 6,000, and 20,000).
Execute both upstream and downstream processes.
Set up, operate equipment, and monitor production processes, including
clean-in-place (CIP) and steam-in-place (SIP) operations and report production in written and electronic documents in accordance with good manufacturing practice (GMPs) and good documentation procedures (GDPs).
Conduct in-process testing pH, conductivity, metabolites, etc.
Who We’re Looking For
We hire across all experience levels and build teams that grow together.
Foundational / Early-Career: No prior biotech experience required. We look for high attention to detail, reliability, and an interest in learning a highly specialized life-science trade.
Intermediate (Level II / III): 1–5 years of experience in regulated manufacturing or clinical labs. Experience with aseptic technique, cleanrooms, or bioreactors is a plus.
Advanced / Senior: 5+ years of GMP experience. Track record of leading complex operations, mentoring others, and owning deviations.
Education: High School Diploma required for all levels; Associate’s or Bachelor’s in STEM preferred for intermediate and advanced roles.
Schedule: Ability to work a rotating 12-hour shift (7 PM – 7 AM -Nights). Our rotation follows a predictable pattern: Work 2 days on, 2 off, 3 on, 2 off, 2 on, 3 off. This ensures consistent time off and includes every other weekend.
Why Lonza Portsmouth
At Lonza, our people are our greatest strength. With 30+ sites across five continents, our globally connected teams work together every day to manufacture the medicines of tomorrow. Our core values of Collaboration, Accountability, Excellence, Passion and Integrity reflect who
we are and how we work together. Everyone’s ideas, big or small, have the potential to improve millions of lives, and that’s the kind of work we want you to be part of.
Innovation thrives when people from all backgrounds bring their unique perspectives to the table. At Lonza, we offer equal employment opportunities to all qualified applicants regardless of race, religion, color, national origin, sex, sexual orientation, gender identity, age, disability, veteran status, or any other characteristic protected by law. If you’re ready to help turn our customers’ breakthrough ideas into viable therapies, we look forward to welcoming you on board.
Ready to shape the future of life sciences? Apply now.