Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. We are developing therapeutics that target muscle and the central nervous system (CNS) to address the root cause of disease. The company is advancing clinical programs for Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1) as well as a preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities. Learn more at https://www.dyne-tx.com/, and follow us on X, LinkedIn and Facebook.
Role Summary:
The Senior Lab Manager works with the Lab Operations Associate Director to provide a smoothly operating laboratory for our scientific personnel. This individual needs to be willing to learn, adapt and be able to perform at a high level in a fast-paced environment.
This role is based in Waltham, MA without the possibility of being a remote role.
Primary Responsibilities Include:
Ensure that all laboratory equipment is properly functioning; coordinate preventative maintenance, repairs, calibrations, purchase of equipment, and coordinate training as needed
Manage and coordinate the maintenance agreements/service contracts for lab equipment and arranging timely maintenance visits working with lab operation associate, scientists and vendors
Oversee all aspects of EHS, including tracking/managing and disposal of chemicals and hazardous/non-hazardous materials, enforcing PPE policy, assist with oversight and management of contract EHS and lab support, maintain permits, participate in and contribute to the IBC and Safety Committee
Support EHS activities related to facilities (fire drills, First Aid Kits, AEDs)
Serve as the Chemical Hygiene Officer
May be assigned responsibilities related to secure material handling in accordance with institutional SOP's
Coordinate with IT to ensure computers, data collection software and associated equipment are functioning in the lab
Work with managers of new hires to coordinate training and provide safety orientation for new lab personnel and visitors to the lab.
Coordinate and support incoming/outgoing domestic and international shipments as needed
Monitoring of gases to support cryo freezers and equipment
ELN management, coordinate training as needed, and the use of other software applications
Interface with Facilities team to maintain the infrastructure serving the labs such as HVAC, exhaust systems, gases, utilities, etc.
Must be willing to come in off hours to resolve lab emergencies if needed
Work with functional areas to generate standing orders as needed, and maintain managed inventories of consumables and reagents
Education and Skills Requirements:
Bachelor’s degree in life science with 5+ years of experience in an industry BL2 wet lab; and 8 years total experience.
Experience working with external vendors and service providers.
Ability to effectively prioritize, shift gears, and execute tasks based on business need.
Excellent decision making, communication and collaboration skills in a cross-functional and multi-level environment demonstrating very strong interpersonal skills
Experience with Electronic Notebook applications, LIMS, and databases
Ability to influence without authority and lead by example
Ability to self-evaluate work for accuracy and completeness
Experience with budget management, contract negotiation, and vendor management
Operational knowledge of and troubleshooting capabilities for common lab equipment
Takes initiative and exhibits independence in identifying and addressing short and long-term opportunities for optimization of lab processes
Current DOT and IATA certifications preferred
Must be able to lift 50 lbs. (this is the weight of one dry ice box) from the floor to approximately bench height
Must be able to sit, stand, walk, bend, stretch and don appropriate PPE for prolonged periods as needed
#LI-Onsite
MA Pay Range
$143,000—$175,000 USD
The pay range reflects the base pay range Dyne reasonably expects to pay for this role at the time of posting. Individual compensation depends on factors such as education, experience, job-related knowledge, and demonstrated skills.
The statements contained herein reflect general details as necessary to describe the principles functions for this job, the level of knowledge and skill typically required, and the scope of responsibility, but should not be considered an all-inclusive listing of work requirements. Individuals may perform other duties as assigned, including work in other functional areas to cover absences or relief, to equalize peak work periods or otherwise balance workload.
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
