Stoke Therapeutics

Stoke Therapeutics is a biotechnology company dedicated to developing RNA-based medicines that address the underlying cause of severe diseases. Their proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) platform aims to increase protein production from healthy genes, thereby restoring functional protein levels and potentially slowing or stopping disease progression. Stoke's initial focus is on haploinsufficiencies and diseases of the central nervous system and the eye, with a specific emphasis on Dravet syndrome, a severe genetic epilepsy.

Stoke's mission is driven by a commitment to patients and an unwavering belief in the transformative potential of their scientific approach. They emphasize a collaborative and inclusive work environment, fueled by a passion for making a difference in the lives of individuals living with severe diseases. The company is rapidly advancing its clinical programs and seeking to expand its pipeline of potential new medicines, with a goal of delivering meaningful therapies for those in need.

Stoke Therapeutics embraces flexibility in work arrangements, prioritizing a balance between individual needs and preferences with the needs of the business. This approach fosters a collaborative and innovative culture while recognizing the importance of work-life balance.

Stoke Therapeutics offers comprehensive and competitive employee benefits. Full-time employees are eligible for health, dental, and vision insurance, life insurance, long and short-term disability insurance, paid parental leave, a 401K program with company match, unlimited vacation time, and an Employee Stock Purchase Program (ESPP). Compensation is market competitive and commensurate with experience, and all positions are bonus and stock eligible.

Stoke Therapeutics is a biotechnology company dedicated to addressing the underlying cause of severe diseases by upregulating protein expression with RNA-based medicines. Their proprietary TANGO (Targeted Augmentation of Nuclear Gene Output) platform aims to increase protein output from healthy genes, thereby restoring functional protein levels and combating diseases like Dravet syndrome and autosomal dominant optic atrophy.

Stoke Therapeutics promotes a collaborative and inclusive culture that values authenticity, respect, and fun. They encourage employees to bring their whole selves to work, embrace diversity, and work together to make a meaningful impact on the lives of patients with severe diseases. The company emphasizes teamwork, open communication, and a sense of urgency driven by their passion for developing life-changing therapies. They believe in fostering a positive and engaging workplace environment that balances the seriousness of their scientific endeavors with opportunities for growth, development, and shared experiences.

Stoke Therapeutics is committed to fostering a diverse and inclusive workplace that celebrates individual differences and encourages employees to contribute to a more equitable world. They recognize the importance of acknowledging and addressing systemic racism and inequity, both within the company and society as a whole. Stoke's efforts include providing employee education on racial inequity, supporting organizations working to address racism, encouraging employees to speak up against violations of equity, and sponsoring programs like Project Onramp to support underrepresented students in the life sciences.