The Work Index by Flexa

Siolta Therapeutics

Siolta Therapeutics is a biotechnology company developing live biotherapeutic products that target the core drivers of disease by leveraging the human microbiome.

https://www.sioltatherapeutics.com/
4.9

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Description

Siolta Therapeutics is a biotechnology company focused on developing live biotherapeutic products (LBPs) and diagnostics for the prevention and treatment of a wide range of diseases, particularly those affecting the maternal-infant axis. The company leverages its deep understanding of the human microbiome and its role in regulating and supporting development, employing a holistic, microbiome-based strategy to create tailored, clinically differentiated live biotherapeutics. Their research and development efforts are concentrated on diseases like atopic diseases, women's health issues, and rare pediatric indications, where limited or no effective treatment options currently exist.

Siolta's approach involves reseeding depleted gut microbiomes with naturally occurring bacteria essential for a healthy immune system. They have established a precision symbiotics platform that combines machine learning, clinical microbiome data analysis, anaerobic microbiology, and translational studies to optimize multi-strain LBPs. Their pipeline includes promising candidates for allergic diseases, recurrent bacterial vaginosis, and necrotizing enterocolitis, with clinical studies underway for several of these conditions. Siolta's innovative approach and commitment to scientific excellence have garnered significant attention and funding, placing them at the forefront of the emerging field of microbiome-based therapeutics.

Mission

Siolta Therapeutics is a company dedicated to developing live biotherapeutics, specifically targeting the human microbiome and its role in disease prevention and treatment. Leveraging their expertise in the human microbiome, particularly its regulatory and developmental functions within the "maternal-infant axis," Siolta aims to create innovative live biotherapeutic products (LBPs) and diagnostics for a wide range of diseases, including atopic diseases, women's health, and rare pediatric indications. Their mission is to reseed the depleted gut microbiome with naturally occurring bacteria, essential for a healthy immune system, ultimately paving the way for a healthier future.

Data-driven
Disruptor
Healthcare
Improving quality of life/health
Science and research driven
Social impact led

Culture

Siolta Therapeutics fosters a collaborative and innovative culture that values scientific excellence and a deep understanding of the human microbiome. The company attracts and retains a highly skilled and diverse team of experts, driven by a shared passion for developing novel live biotherapeutics to improve human health. This dynamic environment encourages open communication, knowledge sharing, and a commitment to advancing microbiome science for a healthier future.

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