Senti Biosciences

Senti Bio is a clinical-stage biotechnology company focused on developing next-generation cell and gene therapies using their proprietary Gene Circuit technology platform. Their mission is to create a new generation of smarter medicines that can outsmart complex diseases, specifically focusing on oncology indications. Senti Bio's Gene Circuits are designed to reprogram cells with biological logic, allowing them to sense their environment, make decisions, and respond accordingly. This approach allows for more precise targeting of cancer cells, sparing healthy cells and potentially leading to more effective and safer therapies.

Senti Bio is headquartered in South San Francisco, California, and boasts a team of experienced professionals in synthetic biology, oncology, and clinical development. Their lead product candidate, SENTI-202, is currently in clinical trials for the treatment of acute myeloid leukemia (AML). The company also has several other programs in development, including partnerships with Celest Therapeutics, Spark Therapeutics, and BlueRock Therapeutics, targeting various cancer types and regenerative medicine applications. Senti Bio is dedicated to pushing the boundaries of cell and gene therapy through innovation and collaboration, striving to deliver life-changing treatments for patients with serious diseases.

Senti Biosciences does not explicitly mention any specifics regarding job flexibility on their careers page.

Senti Bio offers a comprehensive benefits package that supports employees both inside and outside of work. This includes healthy food and snacks, a paid winter holiday, reward and recognition programs, career development support, comprehensive health plans, and instant 401k vesting. These benefits demonstrate the company's commitment to employee well-being and professional growth.

Senti Biosciences is a clinical-stage company dedicated to creating a new generation of smarter medicines for patients suffering from incurable diseases. Their approach involves using synthetic biology to engineer proprietary Gene Circuits, which are novel combinations of DNA sequences designed to reprogram cells with biological logic. These Gene Circuits empower their therapeutics to precisely target and destroy cancer cells while sparing healthy ones, increase specificity to target cells, and control drug expression even after administration. They are focused on developing a pipeline of product candidates that utilize off-the-shelf chimeric antigen receptor natural killer (CAR-NK) cells to address critical challenges in cancer treatment and potentially provide life-saving therapies for patients.

Senti Bio cultivates a culture that values intellectual curiosity, collaboration, and empathy. They encourage a growth mindset, where continuous improvement and setting new standards are embraced. Their emphasis on inclusivity and collaboration ensures that individual success contributes to the overall success of the organization. This culture is grounded in a shared purpose of making a lasting impact on patients' lives, fostering a sense of purpose and intrinsic motivation among employees.

Senti Bio values a diversity of perspectives and creative thinking in order to achieve its ambitious goals. They cultivate an inclusive culture that encourages collaboration and celebrates the unique contributions of each individual. Senti Bio's commitment to diversity, equity and inclusion is reflected in its core values of building and nurturing an inclusive culture and being empathetic, collaborative, intellectually curious and intrinsically motivated.