Pliant Therapeutics

Pliant Therapeutics is a clinical-stage biopharmaceutical company committed to developing innovative therapies for fibrotic diseases. They are driven by a deep understanding of fibrosis biology and focus on inhibiting integrin-mediated activation of TGF-β, a key driver in the development of scar tissue. Pliant's research has led to the development of bexotegrast (PLN-74809), an oral, small molecule, dual-selective inhibitor of the αvβ6 and αvβ1 integrins, currently in late-stage clinical trials for the treatment of idiopathic pulmonary fibrosis (IPF).

Beyond their IPF focus, Pliant is also exploring the potential of their integrin-targeting approach in other fibrotic diseases, such as primary sclerosing cholangitis (PSC), as well as applications in oncology and muscular dystrophy. They have a robust pipeline of investigational drugs and are actively seeking to expand their reach and contribute to the development of new, effective therapies for patients suffering from debilitating fibrotic conditions.

Pliant Therapeutics offers a variety of benefits designed to support a healthy work-life balance. While specific details regarding remote work or flexible schedules are not explicitly stated, the company mentions paid sick and vacation time, paid parental leave, and summer and winter shutdowns, suggesting some level of flexibility. The company also highlights its wellness culture, with employees engaging in fitness activities together, which could imply a supportive environment for flexible work arrangements.

Pliant Therapeutics offers a comprehensive benefits package for their employees, including competitive healthcare plans like medical, dental, and vision insurance. Employees also have access to an Employee Assistance Program and a Modern Health App, a wellness stipend, basic life and accidental death and dismemberment insurance, and short- and long-term disability coverage. Financially, employees can participate in a 401(k) plan with matching contributions, flexible spending accounts, commuter spending accounts, and an Employee Stock Purchase Plan. Other benefits include paid company holidays, sick and vacation time, parental leave, summer and winter shutdowns, an employee referral program, recognition programs, company-sponsored events, and happy hours, demonstrating their commitment to supporting employee well-being both inside and outside the workplace.

Pliant Therapeutics is a clinical-stage biopharmaceutical company focused on developing novel treatments for fibrotic diseases. Their mission is to become the leading fibrosis company by combining world-class expertise in fibrosis biology, chemistry, and technology to develop best-in-class, tissue-specific inhibitors of fibrotic diseases, ultimately transforming the lives of patients suffering from these debilitating and deadly conditions.

Pliant Therapeutics promotes a culture focused on teamwork, collaboration, and innovation. They value trust, both within the team and in the science they pursue, and encourage open communication and knowledge sharing. The company emphasizes diversity and inclusion, believing that varied perspectives lead to better outcomes and creative problem-solving. Their commitment to employee well-being is evident in their benefits package, which includes wellness programs and flexible work arrangements.

Pliant Therapeutics is committed to fostering an inclusive workplace where diverse backgrounds, ideas, and perspectives drive innovation and contribute to the company's mission to combat fibrotic diseases. They believe that a culture built on trust, respect, and collaboration, along with varied thoughts and inputs, will ultimately lead to better outcomes for both their employees and the patients they serve. This commitment to diversity, equity, and inclusion is reflected in their recruitment, training, and development programs, as well as their efforts to create a welcoming and supportive environment for all.