The Work Index by Flexa

Photys Therapeutics

Photys Therapeutics is a biotechnology company developing a new class of bifunctional small molecules to precisely modulate and repair disease-driving proteins.

https://www.photys.com/
4.8

/10

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Description

Photys Therapeutics is a biotechnology company focused on developing a novel class of bifunctional small molecules called Phosphorylation-Inducing Chimeric Small Molecules (PHICS). These molecules work by enhancing the pairing of specific kinases, enzymes responsible for protein phosphorylation, with disease target proteins. By inducing precise phosphorylation, PHICS can modulate key protein functions, ultimately restoring protein function, repairing signaling pathways, and amplifying endogenous disease-fighting mechanisms.

Photys was co-founded by Amit Choudhary, a leading bifunctional chemist from the Broad Institute, and the Longwood Fund. The company boasts a distinguished Scientific Advisory Board comprising scientists and drug developers from renowned institutions like MIT, Salk Institute, and Berkeley. Photys recently secured $75 million in Series A funding, signaling strong investor confidence in their technology and its potential to address a wide range of diseases.

Mission

Photys Therapeutics is a biotechnology company focused on developing a new class of bifunctional small molecules to precisely control protein post-translational modifications, specifically phosphorylation. Their technology, called Phosphorylation-Inducing Chimeric Small Molecules (PHICS), aims to modulate and repair disease-driving proteins by inducing precise phosphorylation at native and/or non-native sites. Photys' mission is to unlock the potential of these molecules to restore protein function, repair signaling, and amplify endogenous disease-fighting mechanisms, ultimately leading to the development of innovative therapies for a wide range of diseases.

Disruptor
Healthcare
Improving quality of life/health
Science and research driven
Soonicorn

Culture

Photys Therapeutics cultivates a culture of innovation and collaboration, driven by a team of highly skilled scientists and drug developers. The company values scientific excellence and embraces a multidisciplinary approach to research, drawing on expertise from various fields. This collaborative environment is fostered by the presence of a distinguished scientific advisory board, comprised of leading scientists from renowned institutions, who provide guidance and support.

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