The Work Index by Flexa

PepGen

PepGen is a clinical-stage biotechnology company focused on developing transformative therapies for severe neuromuscular and neurological diseases.

https://www.pepgen.com/
5.2

/10

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Description

PepGen is a clinical-stage biotechnology company focused on developing a new generation of oligonucleotide therapies to treat severe neuromuscular and neurological diseases. Their proprietary Enhanced Delivery Oligonucleotide (EDO) platform utilizes cell-penetrating peptides to improve the delivery and activity of conjugated oligonucleotide therapeutics. This innovative approach addresses the challenges of delivering these therapies to the heart and skeletal muscle, the key tissues affected in diseases like Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1).

PepGen's commitment to scientific innovation and patient impact drives their mission to develop truly transformative therapies. They are actively building a pipeline of disease-modifying oligonucleotide candidates for DMD and DM1, and are expanding their research into additional neuromuscular and neurological indications. Their EDO platform has demonstrated encouraging results in preclinical studies, showing the potential to halt, slow, or potentially reverse the progression of these debilitating diseases. With a focus on robust clinical trials and a dedicated team of scientists and industry leaders, PepGen is poised to change the future of treatment for individuals living with neuromuscular and neurological disorders.

Flexibility

PepGen offers unlimited paid vacation time, a minimum requirement of two weeks off per year, and 10 paid holidays. They also offer 12 weeks of paid parental leave for the primary caregiver and 6 weeks for the secondary caregiver. This demonstrates a commitment to work-life balance and flexibility, though specific details on remote work options or flexible scheduling are not mentioned.

Benefits

PepGen offers a comprehensive benefits package designed to support its employees. They provide unlimited paid time off, 10 paid holidays per year, and a generous parental leave policy of 12 weeks paid for the primary caregiver and 6 weeks paid for the secondary caregiver. Additionally, PepGen offers a choice of medical and dental plans through Blue Cross Blue Shield of MA, a health reimbursement arrangement, and a vision plan. Financial benefits include a 401k with a 3% employer contribution, as well as student loan repayment and 529 contribution options. PepGen also provides a $200 monthly ThrivePass wellness allowance for employees to use towards health, fitness, charity, travel, and other needs.

Enhanced parental leave

Mission

PepGen is a clinical-stage biotechnology company dedicated to developing a new generation of oligonucleotide therapies for the treatment of severe neuromuscular and neurological diseases. Driven by their proprietary Enhanced Delivery Oligonucleotide (EDO) platform, they aim to transform patient outcomes by safely and effectively targeting the root cause of these debilitating diseases, starting with Duchenne muscular dystrophy (DMD) and myotonic dystrophy type 1 (DM1). Their EDO technology overcomes the delivery challenges of previous oligonucleotide therapies, achieving deep tissue penetration and high uptake in key muscle tissues. PepGen is committed to creating truly transformative therapies that result in clinically meaningful outcomes for individuals living with these devastating diseases.

Disruptor
Healthcare
Improving quality of life/health
Science and research driven
Social impact led

Culture

PepGen fosters a dynamic, enthusiastic, and respectful work environment where collaboration, scientific rigor, and a commitment to improving the lives of patients with rare neuromuscular diseases are highly valued. They strive to create an inclusive culture where employees feel empowered to contribute their expertise and are supported by competitive benefits, including unlimited paid vacation time and a generous wellness allowance.

Collaborative
Entrepreneurial

DE&I

PepGen is committed to fostering a dynamic, enthusiastic, and respectful working environment within their highly motivated team. Their core values of research, integrity, innovation and responsibility drive their inclusive company culture. They offer a competitive benefits plan which includes paid time off, holidays, parental leave, health benefits, financial benefits, and a wellness allowance, all designed to support their diverse team.

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