OnKure Therapeutics

OnKure Therapeutics is a clinical-stage biopharmaceutical company focused on discovering and developing precision medicines that target biologically validated drivers of cancer. Their approach emphasizes structure-based drug design, enabling them to create a robust pipeline of tumor-agnostic candidates with optimal tolerability and efficacy. OnKure's commitment to innovation and advancing drugs to improve patient care is evident in their experienced team of scientists and their focus on developing differentiated therapies.

OnKure is currently developing OKI-219, a selective PI3KαH1047R inhibitor, as its lead program. They are also exploring several other oncology targets to expand their pipeline, with a focus on creating best-in-class drug candidates with a clear path to clinical proof of concept. Their leadership team has a long track record of success in drug discovery, having collectively contributed to over ten new approved drugs and 30+ INDs. Their expertise and commitment to precision medicine position OnKure as a leading innovator in the fight against cancer.

OnKure offers a flexible work environment, with the Senior Scientist position primarily office-based. However, there are opportunities for laboratory work and occasional travel, depending on the specific project requirements.

OnKure Therapeutics offers a comprehensive benefits package to its employees, encompassing medical, dental, and vision insurance, as well as FSA/HSA options. The company also provides disability insurance, life and AD&D insurance, and an employee assistance program. OnKure encourages financial security with a 401(k) plan that includes an employer match. Additionally, they offer paid parental leave, flexible time off, and a competitive compensation package with performance-based bonuses and stock options.

OnKure Therapeutics is a clinical-stage biopharmaceutical company committed to discovering and developing best-in-class precision medicines that target biologically validated drivers of cancer, particularly those underserved by existing therapies. They use a proven structure-based drug design platform to build a robust pipeline of tumor-agnostic candidates that are designed to achieve optimal tolerability and efficacy, ultimately aiming to improve clinical outcomes for cancer patients.

OnKure Therapeutics fosters a collaborative and purpose-driven culture, prioritizing cross-functional learning and rewarding employees with competitive benefits. The company emphasizes urgency and a strong sense of purpose in getting drugs to patients in need, creating an environment where high expectations are set for both individuals and the team as a whole.

OnKure Therapeutics is committed to building a diverse, equitable and inclusive workplace. The company values the contributions of individuals from all backgrounds and believes that a diverse workforce fosters innovation and creativity. OnKure actively seeks to attract and retain a diverse workforce by implementing initiatives such as employee resource groups, diversity and inclusion training, and inclusive hiring practices. The company is dedicated to creating a work environment where all employees feel respected, valued, and empowered to succeed.