The Work Index by Flexa

iECURE, inc.

iECURE is a gene editing company focused on developing therapies for liver disorders with significant unmet needs.

https://iecure.com/
5.3

/10

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Description

iECURE, Inc. is a gene editing company dedicated to developing curative treatments for rare, devastating liver disorders. The company utilizes a mutation-agnostic in vivo gene insertion approach, meaning their therapies can address a broad range of genetic mutations causing these diseases. This innovative technology involves delivering healthy copies of disease-causing genes directly into patients' chromosomes, offering the potential for long-term, stable expression and, ultimately, a cure.

iECURE's initial focus lies on urea cycle disorders, specifically ornithine transcarbamylase (OTC) deficiency and citrullinemia type 1. They also have programs for phenylketonuria (PKU) and are actively evaluating new technologies and therapeutic areas. The company is built on a foundational collaboration with the University of Pennsylvania's Gene Therapy Program, leveraging their expertise in vector engineering, early-stage development, and gene editing manufacturing. iECURE is committed to advancing their therapies through clinical trials and regulatory approval to ensure safe and timely access to their medicines for patients in need.

Mission

iECURE is a gene editing company dedicated to developing treatments for liver disorders with high unmet needs. They focus on mutation-agnostic in vivo gene editing, meaning they can insert healthy copies of disease-causing genes into a patient's chromosomes, regardless of the specific mutations present. Their goal is to provide long-term, stable expression of these genes in patients, offering potentially curative treatments and ultimately transforming the lives of those suffering from devastating liver diseases.

Disruptor
Healthcare
Improving quality of life/health
Science and research driven
Social impact led
Tech for good

Culture

iECURE fosters a culture of collaboration, innovation, and patient-centricity. Their team of experts, driven by a shared mission to transform lives, works together to bring potentially curative treatments to patients in need. They value a deep level of collaboration at all levels, inspiring an environment that encourages creativity, execution, and unwavering commitment to making a difference in the lives of those they serve.

Collaborative
People-first
Progressive
Supportive

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