HotSpot Therapeutics, Inc.

HotSpot Therapeutics is a biotechnology company focused on pioneering a new approach to allosteric drug discovery. They believe that by unlocking "natural hotspots" on proteins, they can create differentiated medicines for patients. Their proprietary platform, Smart Allostery™, integrates structure-function, pharmacology, chemistry, and AI capabilities to systematically uncover and drug these natural hotspots.

HotSpot Therapeutics is focused on developing novel allosteric medicines for the treatment of cancer and autoimmune diseases. They have a pipeline of therapeutic candidates that address key challenges for targets with deep genetic and/or biological validation. Their pipeline is further enabled by biomarker-driven, patient-targeted approaches. HotSpot Therapeutics is led by a team of seasoned drug hunters with substantial industry and R&D expertise.

HotSpot Therapeutics provides a rewarding, fast-paced but caring environment where team members have significant flexibility to shape how they work and how best to achieve the goals of the company. They have an international footprint with team members in the US, Europe and Asia.

HotSpot Therapeutics offers a rewarding, fast-paced, and caring work environment, with significant flexibility for employees to shape their work and achieve company goals. The company has an international footprint, with team members in the US, Europe, and Asia. HotSpot is an equal opportunity employer, committed to diversity and inclusion. They require employees to be fully vaccinated against COVID-19 and comply with local vaccination requirements.

HotSpot Therapeutics is a biotechnology company pioneering a new approach to allosteric drug discovery by unlocking the on/off switches on proteins called "natural hotspots" to enable differentiated medicines for patients. Their Smart Allostery™ platform integrates structure-function, cutting-edge pharmacology, tailored chemistry, and deep AI capabilities to systematically uncover and drug these natural hotspots. This innovative approach aims to discover novel allosteric medicines that offer new ways to treat cancer and autoimmune diseases where there remains a significant unmet need.

HotSpot Therapeutics promotes a culture of rebellious innovation, where employees are encouraged to challenge conventional thinking and strive to make a lasting contribution to society. They value collaboration, trust, and human interaction, believing that innovation thrives in an environment where egos are checked at the door and team members assume the best about each other. They are also committed to pragmatism and delivering on their promises, constantly pushing the boundaries of traditional scientific approaches.

HotSpot Therapeutics is committed to fostering a diverse, equitable, and inclusive workplace where all employees feel valued and respected. They believe that a diverse team of passionate individuals, who are comfortable adjusting their perspectives, thinking big, testing bold ideas, and celebrating collective wins, leads to greater innovation. HotSpot embraces individuals from all backgrounds and experiences and aims to create an environment where everyone feels welcome and has the opportunity to succeed.