Generation Bio

Generation Bio is a biotechnology company dedicated to developing innovative genetic medicines that provide long-lasting, redosable treatments for individuals living with rare and prevalent diseases. They aim to achieve this through two distinct and complementary platforms: a potent and highly selective cell-targeted lipid nanoparticle (ctLNP) delivery system and a novel, immune-quiet DNA (iqDNA) cargo produced by a scalable capsid-free manufacturing process. By leveraging these platforms, Generation Bio seeks to overcome the limitations of existing genetic medicine approaches, including short-lived expression, limited targeting, and burdensome manufacturing processes.

The company has made significant advancements in both ctLNP and iqDNA, including demonstrating highly selective delivery to T cells in vivo and showing that iqDNA can evade innate immune detection in both mice and non-human primates. With these breakthroughs, Generation Bio is poised to develop a new generation of genetic medicines that could revolutionize the treatment of a wide range of diseases and improve the lives of millions of patients worldwide.

Generation Bio offers a flexible work environment that allows for both in-office and virtual work. They support employees in bringing their true selves to work, fostering a culture that is free and connected. The company provides a well-stocked café and intentional spaces for gathering, as well as frequent professional development opportunities. Generation Bio encourages everyone to take advantage of their flexible vacation policy and also shuts down the entire office for a week each July and December.

Generation Bio offers comprehensive employee benefits aimed at fostering a thriving work-life balance. These benefits include comprehensive medical, dental, and vision coverage, flexible vacation time with two weeks of company-wide shutdown, parental, family, medical, maternity, and bonding leave. To promote financial well-being, they offer a 401K program, disability and life insurance, Flexible Spending Accounts (FSA) and Health Savings Accounts (HSA), as well as commuting and device assistance, tuition reimbursement, student loan refinancing, and an Employee Assistance Program. Additionally, they encourage employees to take every holiday and utilize their flexible vacation policy, with the entire office shutting down for a week each July and December.

Generation Bio is a biotechnology company dedicated to innovating non-viral genetic medicines that provide durable and redosable treatments for people living with both rare and prevalent diseases. They are developing two platforms: a cell-targeted lipid nanoparticle (ctLNP) delivery system and an immune-quiet DNA (iqDNA) cargo. The company's mission is to extend the reach of genetic medicine to more people living with more diseases, around the world.

Generation Bio fosters a collaborative and open work environment where individuality is celebrated. The company prioritizes transparency, inclusivity, and support, providing employees with a sense of community and shared purpose. Their new headquarters reflects these values with open spaces, cross-functional team arrangements, and spaces designed for collaboration. They also offer a range of benefits aimed at supporting employee well-being, including comprehensive health coverage, flexible vacation time, and company-wide closures during the summer and winter holidays.

Generation Bio champions a diverse and inclusive culture, recognizing that a variety of perspectives fosters creativity, innovation, and better decision-making. They celebrate differences in backgrounds, skillsets, and ideas, believing this creates a stronger community. Their new headquarters, known as "301," is intentionally designed to promote collaboration and openness, with cross-functional teams and a focus on shared spaces. They prioritize a welcoming and supportive environment for all employees, actively encouraging both in-office and virtual working, and offering a range of benefits to support physical, mental, and financial well-being.